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Genetics (Mendelian)

Page history last edited by Shu-Yee Chen 4 years, 7 months ago

Unit: Mendelian Genetics

 

 

Big Idea:

Living systems store, retrieve, transmit and respond to information essential to life processes. 

 

Enduring Understanding:

3.A.2: In eukaryotes, heritable information is passed to the next generation via processes that include the cell cycle and mitosis or meiosis plus fertilization.

3.A.3: The chromosomal basis of inheritance provides an understanding of the pattern of passage (transmission) of genes from parent to offspring.

3.A.4: The inheritance pattern of many traits cannot be explained by simple Mendelian genetics.

3.C.2: Biological systems have multiple processes that increase genetic variation.

 

Required Reading:

  • Campbell: Chapter 13 (Should be review), 14,15

  • Labs: Sordaria Meiosis Lab 

  • ARTICLES/CASE STUDY

    • Video: Ghost in Your Genes 

 

 

Learning Objectives:By the end of this unit, you should be able to.... 

1.

Compare and contrast sexual and asexual reproduction. (Ch 13.1)

2.

Explain the role of meiosis and fertilization in sexually reproducing organisms. (Ch 13.2) 

3.

Describe the importance of homologous chromosomes to meiosis. (Ch 13.2)

4.

Explain how the chromosome numbers is reduced from diploid to haploid through the stages of meiosis. (Ch 13.3) 

5.

Compare and contrast mitosis and meiosis, be able to explain at least three important differences. (Ch 13.3) 

6.

Explain the significance of crossing over, independent assortment, and random fertilization to increasing genetic variability. (Ch 13.4)

7.

Be familiar with the following terms associated with genetic problems: P, F1, F2, dominant recessive, homozygous, heterozygous, phenotype, and genotype. (Ch 14.1)  

8.

Utilize the laws of probability to solve Mendelian genetics problems and read a pedigree. (Ch 14.1 & 14.2 & 14.3) 

9.

Explain the difference between an allele vs a gene. (Ch 14.2)

10.

Explain how the chromosome theory of inheritance connects the physical movement of chromosomes in meiosis to Mendel's laws of inheritance. (Ch 15.1) 

11.

Solve sex-linked inheritance problems and explain the phenotype of individuals with X-linked disorders. (Ch 15.2)

12. Explain how gene linkage and recombinants can be used to understand genetic variance in each generation. (Ch 15.3)
13. Predict how the alteration of chromosome numbers or structure can cause genetic disorders. Be able to give some examples of genetic disorders in human caused by chromosomal issues. (Ch 15.4)
14. Provide examples of non-Mendelian inheritance such as genomic imprinting and inheritance of mitochondrial DNA. (Ch 15.5) 
15. Provide examples of how meiosis and crossing-over events increase genetic variation. (Lab)
16. Use the data of Sordaria to calculate map distance and practice Chi-Square analysis. (Lab)

 

 

 

Vocabulary

Below is a list of vocabularyterms used in this unit. By the end of the unit, you will be able to write a working definition of each term and correctly use each term. 

 

gene locus asexual reproduction
sexual reproduction karyotype somatic cells
diploid homologous autosomes
sex chromosomes life cycle haploid
gametes meiosis fertilization
zygote crossing over  recombinant chromosomes
law of segregation alleles heterozygotes
dominant recessive homozygotes
true-breeding law of independent assortment dihybrids
multiplication rule complete dominance incomplete dominance
codominance polygenic inheritance pleiotropy
chromosome theory of inheritance sex-linked genes X-linked
Barr body parental types recobinant types
linked genes crossing over linkage map
aneuploidy nondisjunction trisomy
monosomy polyploidy genetic imprinting

 


Worksheets/Labs/Handouts: 

 

Extra Worksheets/Notes from past years/review/challenge materials: 


Supplement Material/Websites:

Home Page

 

 

 

 

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